April 2024: Habilitation to Direct Research en Sciences du Mouvement Humain
- Title. Cardiovascular and Respiratory Adaptations to Deficit in Dioxygen: For Health and Performance.
- Members of the panel.
- Pr. Philippe CONNES, Université Claude Bernard Lyon 1 (France), Reviewer
- Dr. Dan GORDON, Anglia Ruskin University (UK) et Université Paris-Saclay (France), Examiner
- Pr. Stéphane PERREY, Université de Montpellier (France), Reviewer
- Pr. Claire THOMAS-JUNIUS, Université d’Evry Paris-Saclay (France), Examiner
- Pr. Alain VARRAY, Université de Montpellier (France), Examiner and President of the panel
- Pr. Agnès VINET-JULLIAN, Université d´Avignon et des Pays du Vaucluse (France), Reviewer
- Abstract. This HDR thesis provides a comprehensive synthesis of my past, current, and future research work, as well as the other activities in my academic career. The first part of the thesis is dedicated to my research which mainly addresses the cardiovascular and respiratory adaptations to dioxygen deficit during exercise. The first chapter presents a set of studies conducted at the Anglia Ruskin University (Cambridge, UK) and which have shown the dependency of cardiovascular and respiratory adaptations – as observable through the occurrence of the plateau of VO2max – on specific exercise modalities surrounding athletes’ maximal effort tests. In the second chapter is presented a set of studies conducted at the University-Hospital of Angers (France), which have demonstrated the effectiveness of walking transcutaneous oxygen pressure (tcpO2) and Global Positioning System (GPS) in assessing the level of ischemia during the walk in patients suffering from Peripheral Arterial Disease (PAD). The third chapter is devoted to my current research at the Université Paris-Saclay (France), which consists of testing the effects of training with Ischemic Preconditioning (IPC) and Blood Flow Restriction (BFR) on the cardiovascular and respiratory adaptations and responses of diabetic patients and athletes. The fourth chapter presents my research perspectives on IPC and BFR. Following this first part dedicated to my research, the second part of the thesis summarises my other academic activities, which include substantial responsibilities and organisational charges covering both the scientific and educational aspects of my profession and show my ability to supervise and coordinate research programmes.
June 2015: Ph.D. [Link]
- Title. Characterization of the walking impairment in peripheral arterial disease patients with intermittent claudication: Contributions of innovative méthodologies i.e., GPS and exercise TcPO2.
- Members of the panel.
- Pr. Sylvain DURAND, Université du Mans (France), Examiner
- Pr. Pierre ABRAHAM, Université d’Angers (France), PhD supervisor
- Pr. Daniel Rivère, Université de Toulouse (France), Reviewer
- Pr. Agnès VINET-JULLIAN, Université d´Avignon et des Pays du Vaucluse (France), Reviewer and President of the panel
- Abstract. Peripheral Arterial Diseased (PAD) is a major concern regarding their clinical care since a revascularization intervention is indicated below the cut-off point of 300 m. In clinical routine, MWD is usually assessed with clinical questionnaires, a highly subjective method, and with walking treadmill tests that are design-dependent and that hardly reproduce the usual pain of the patients during the walk. Therefore, the aim of this doctoral work is to test the validity of innovative methodologies based on GPS and Transcutaneous Pressure in Oxygen (TcPO2) during a treadmill test with respect to the assessment of the functional limitation in PAD patients. The first study shows that scores of the Estimation of Ambulatory Capacity by History-Questionnaire and MWD that is declared by the patients are more related to the GPS-measured MWD (that reflects the spontaneous walking pattern) than to the scores of the Walking Impairment Questionnaire, the 6-min walking test, and the walking treadmill test. The second study evidences the relevance of the use of TcPO2 during a walking treadmill test in detecting ischemia during exercise among patients with normal Ankle to brachial Index. The third and fourth studies show the reliability of the GPS as well as its applicability to the evolvement of the walking parameters following revascularization. Finally, the fifth study suggests that the GPS-accelerometer coupling is able to estimate the energy expenditure of PAD patients. To conclude, actimetry (e.g., GPS, accelerometer) and exercise TcPO2 are valid and reliable methods to evaluate the walk of PAD patients.
- Key Words. Peripheral Arterial Diseased; claudication ; walking test; exercise TcPO2; Global Positioning System; Energy Expenditure.
2010: Postgraduate in Sport Sciences
- Adapted Physical Activity course
- Distinction: mention assez bien
- University of Montpellier 1, Fr
2008: Graduate in Sport Sciences
- Adapted Physical Activity course
- Distinction: mention assez bien
- University of Montpellier 1, Fr